The histopathological spectrum of acute generalized exanthematous pustulosis (AGEP) and its differentiation from generalized pustular psoriasis

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The histopathological spectrum of acute generalized exanthematous pustulosis (AGEP) and its differentiation from generalized pustular psoriasis.

BACKGROUND Acute generalized exanthematous pustulosis (AGEP) represents a severe, acute, pustular skin reaction that is most often induced by drugs. AGEP can be difficult to differentiate from generalized pustular psoriasis (GPP) both clinically and histopathologically. We present a systematic description of the histopathological spectrum of AGEP and GPP with a focus on discriminating features....

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Acute generalized exanthematous pustulosis (AGEP) in Singapore

Results There were 20 cases of AGEP that were seen during the study period. Of which there are 8 males (40%) and 12 (females (60%) with a mean age of 60 years (Range : 24-85 years). In addition to extensive pinpoint pustules, other cutaneous features included facial edema, target-like lesions with rim of pustules and edema bulla. Common laboratory derangement included leukocytosis, eosinophilia...

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Acute generalized exanthematous pustulosis (AGEP). Case report.

Acute Generalized Exanthematous Pustulosis (AGEP) is a drug-induced dermatosis characterized by an acute episode of sterile pustules over erythematous-edematous skin. It is accompanied by an episode of fever, which regresses a few days after discontinuation of the drug that caused the condition or as a result of corticosteroid treatment. The main triggering drugs are antibiotics, mainly beta-la...

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Acute generalized exanthematous pustulosis (AGEP) induced by azithromycin.

Maria V. Campanón-Toro1, Omar Sierra1, Esther Moreno1,2,3, Miriam Sobrino-García1, Maria T. Gracia-Bara1,2 and Ignacio Dávila1,2,3 1Allergy Department, University Hospital of Salamanca, 37007 Salamanca Spain, 2 IBSAL (Instituto Biosanitario de Salamanca), University Hospital of Salamanca, Spain, and 3Department of Biomedical and Diagnostic Sciences, Salamanca Medical School, University of Salam...

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Acute generalized exanthematous pustulosis (AGEP)--a clinical reaction pattern.

BACKGROUND A wide range of diseases or reactions can cause pustular eruptions of the skin. In this spectrum there seems to be a subgroup with characteristic clinical features and a typical course which is mostly caused by drugs for which the term acute generalized exanthematous pustulosis (AGEP) has been established. OBJECTIVE To describe the clinical features of AGEP. METHODS The authors' ...

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ژورنال

عنوان ژورنال: Journal of Cutaneous Pathology

سال: 2010

ISSN: 0303-6987

DOI: 10.1111/j.1600-0560.2010.01612.x